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Donor Embryo & Donor Sperms

Embryo donation or the sperm donation is the process of donating a sperm or the embryo to the infertile couple for the purpose of artificial insemination. It is the type of ART followed, when the own embryo or sperms cannot be produced due to various reasons. Donor eggs and donor sperms together can be used to produce embryo, which can be used to donate to the infertile female.

The factors indicating Donor Embryo or Donor Sperms are

In Females
  • Women with premature ovarian follicle.
  • Older women or near menopausal women.
  • Failure to respond with superovulation regimen or with poor ovarian reserve.
  • Women with repeated failure of ART cycles.
  • Genetic diseases.

In Males
  • With low spermatic count less than or below 5 million sperms/mL.
  • If the sperms are weak and have decreased motility rate.

Procedure

In the donor embryo procedure, the female donating her embryo should be screened for the diseases and consent should be taken for artificial insemination. In this case the fertilized embryo is donated to the infertile couple, which is implanted into the uterus of the infertile female to achieve pregnancy. This is usually done on anonymous basis both recipient and the donor do not know each other.

For sperm donation, the sperms of the person is collected from the sperm bank or fertility clinic. Then by the methods of ICSI (Intracytoplasmic sperm injection) or by IVF methods, insemination is done in the culture plates along with the eggs for fertilization and the fertilized embryo is embedded into the uterus of the female.

Factors Affecting Success Rates

Embryo donation and the sperm donation increases the success rates of pregnancy with 60-80% after the treatment. Successful implantation needs a coordination between the embryo and endometrium. Estrogen therapy is simultaneously started in the recipient during the retrieval time. Oocytes and embryo can be further cryopreserved at -196℃ under liquid nitrogen for future fertility treatments.

Donor Selection

There’s always an issue related to donor eggs or embryos or sperms, as this arises the question of legal, ethical and social issues. So the criteria for the selection of the donor are

  • Sister or brother or family person or friend aged between 21-34 years.
  • One undergoing with laparoscopic sterilization with financial compensation.
  • Healthy, well-educated and free from infectious and genetic diseases.
  • One who is willing to donate for monetary benefits.
  • Even sperms and eggs can be taken from fertility clinics, as the donor will be unknown but healthy and screened for diseases.